Journal: Cancer Science
Article Title: Tumor‐derived exosomal proteins as diagnostic biomarkers in non‐small cell lung cancer
doi: 10.1111/cas.13862
Figure Lengend Snippet: Alpha‐2‐HS‐glycoprotein (AHSG) and extracellular matrix protein 1 (ECM1) as non‐invasive biomarkers for non‐small‐cell lung cancer (NSCLC). A, The expression level of AHSG and ECM1 detected by Western blotting in NSCLC and healthy individuals. B, The concentration of exosomal AHSG in NSCLC patients and healthy donors. C, The concentration of exosomal AHSG in healthy donors (n = 46), NSCLC patients (n = 122), early stage of NSCLC (n = 31). **P < 0.01, ****P < 0.0001. D, The concentration of exosomal ECM1 in NSCLC patients and healthy donors. E, The concentration of exosomal ECM1 in healthy donors (n = 46), NSCLC patients (n = 109), early stage of NSCLC (n = 28). *P < 0.05, ***P < 0.001
Article Snippet: Blood serum from patients with NSCLC and healthy individuals was analyzed using a Human AHSG ELISA Kit (KE00097; Proteintech, Rosemont, IL, USA) and Human ECM‐1 ELISA Kit (ELH‐ECM1; RayBiotech, Atlanta, GA, USA) according to the manufacturer's instructions.
Techniques: Expressing, Western Blot, Concentration Assay